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副教授

张文平

发表于:2016-06-30  浏览人数:

张文平

别:男

出生年月:196901

称:副教授

组: 生物制药

室: 6-417

话: 0571-86843199

电子邮件:wenpingzhang@zstu.edu.cn

主要学习工作经历

1. 20148-20159 美国德克萨斯大学医学院 访问学者

2. 20056-至今 浙江理工大学生命科学学院

3. 20069-20106 浙江大学生命科学学院 生物化学与分子生物学 博士;20029-20056 中国药科大学药学院 药理学 硕士;19879-19916 吉林农业大学中药材学院 药用动物 学士

主要学术及社会兼职

1. 中国药学会、中国生物化学与分子生物学、浙江省药学会、浙江省生物化学与分子生物学会员

2. 浙江中奇生物药业股份有限公司高级顾问

3. 怡生堂大药房连锁有限公司执业药师

主要研究方向

1.神经分子药理学

2.家蚕生物反应器制药

获奖与荣誉

1. 浙江省自然科学学术二等奖1

2. 浙江省自然科学学术三等奖1

科研教学项目

1. 2016.1-2017.12 《提高多肽类药物口服吸收的新型辅料的研究与开发》(浙江省科技厅公益技术项目,主持)

2. 2011.01-2013.12家蚕生物反应器生产的蛋白药物BmrhGM-CSF口服吸收机制的研究(浙江省自然科学基金项目,主持)

3. 2012.07-2014.07提高家蚕免疫力的新型蚕药BmTHY的研究与开发(浙江省科技厅公益技术项目,主持)

4. 2010.09-2012.12家蚕生物反应器生产的蛋白药物BmrhGM-CSF口服吸收的研究(浙江省教育厅项目,主持)

5. 2007.01-2009.12 家蚕生物反应器蛋白质药物规模化制备技术(国家863项目,第二参与人)

专著论文

1. Li Si, Fei JingJing, Cheng DanDan, Jin Yongfeng, Zhang Wenping, Zhang Yaozhou, Lv Zhengbing. Bioinformatics, tissue distribution, and subcellular localization analyses of fk506 binding protein 12b from silkworms. Arch Insect Biochem Physiol2016912):109-123

2. Zhang Wenping, Wang Jian, Zhang Chen, Fang Qiang, Shu Jianhong, Li Si, Jin Jia, Wang Dan, Nie Zuoming, Lv Zhengbing, Zhang Yaozhou. Synergetic Protein Factors That Improve rhGM-CSF Absorption via an Oral Route Exist in Silkworm Pupae. Mol Pharm2015,125:1347-1355

3.Nie Zuoming, Zhu Honglin, Zhou Yong, Wu Chengcheng, Liu Yue, Sheng Qing, Lv Zhengbing, Yu Wei, Zhang Wenping, Jiang Caiying, Xie Longfei, Zhang Yaozhou, Yao Juming. Comprehensive profiling of lysine acetylation suggests the widespread function is regulated by protein acetylation in the silkworm, Bombyx mori. Proteomics20151518):3253-3266

4.Li Yuanyuan, Wang Weidong, Cheng Dandan, Wang Tao, Zhang Wenping, Lv Zhengbing, Wu Wutong, Shu Jianhong. A New Member of the TBC1D15 Family from Chiloscyllium plagiosum: Rab GTPase-Activating Protein Based on Rab7 as a Substrate. Mar Drugs, 2015,135:2955-2966

5. Zhang Jie, Liu Yunlong, Zhang Xiaofei, Pan Jingjing, Nie Zuoming, Zhang Wenping, Wu Wutong, Zhu Huili, Lv Zhengbing. The identification of microRNAs in the whitespotted bamboo shark (Chiloscyllium plagiosum) liver by Illumina sequencing. Gene, 2013,5271:259-265

6. Liu Yunlong, Chen Ying, Chen Jianqing, Zhang Wenping, Sheng Qing, Zhang Yaozhou, Wu Wutong, Wang Lisha, Indran Inthrani Raja,Li Jun, Qian LianLv Zhengbing. A shark liver gene-derived active peptide expressed in the silkworm, Bombyx mori: preliminary studies for oral administration of the recombinant protein. Marine Drugs, 2013,115:1492-1505

7. Zhang Wenping, Zhang Changrong, Lv Zhengbing, Fang Dailing, Wang Dan, Nie Zuoming, Yu Wei, Lan Hanglian, Jiang Caiying, Zhang Yaozhou. Molecular characterization, tissue distribution, subcellular localization and actin-sequestering function of a thymosin protein from silkworm. PLos One, 2012,72:e31040-e31040

8. Lv Zhengbing, Zhang Xufang, Liu Lili, Chen Jian, Nie Zuoming, Sheng Qing, Zhang Wenping, Li Jun, Zhang Yaozhou. Characterization of a gene encoding prohibitin in silkworm, Bombyx mori. Gene, 2012,5022:118-124

9. Zhang Wenping, Lan Hanglian, Wu Tao, Jiang Caiying, Lv Zhengbing, Nie Zuoming, Wu Xiangfu, Zhang Yaozhou. Expression analysis and characteristics of hypothetical protein BmLOC778500 from silkworm, Bombyx mori. Afr J Biotechnol, 2011,1019:3753-3761

10.Zhang Wenping, Lv Zhengbing, Nie Zuoming, Chen Guogang, Chen Jian, Sheng Qing,Yu Wei, Jin Yongfeng, Wu Xiangfu, Zhang Yaozhou, Bioavailability of orally administered rhGM-CSF: a single-dose, randomized, open-label, two-period crossover trial. PLoS One, 2009,45:e5353-e5353