徐科，工学博士，讲师兼实验师，实验管理中心副主任，院工会主席。

研究方向：智能药物控释载体、肿瘤靶向治疗和凝胶生物传感器。

已发表论文19余篇，其中SCI收录论文11篇。主持或参与各类科研项目11项。担任ACS Applied Materials & Interfaces、Gels等国际杂志审稿人

联系方式：xk49677559@163.com

发表论文：

[1] Xu, K.; Wang, L.; Shan, W.; Gao, K.; Wang ,J.; Zhong, Q.; Zhou, W. Highly Stretchable and Self-adhesive Wearable Biosensor based on Nanozyme Catalyzed Conductive Hydrogels Mimicked by Skin Structure. ACS Applied Polymer Polymer Materials.2024, 6, 2188-2200.(SCI二区，封面论文)

[2] Xu, K.; Shan, W.; Hu, N.; Wang, J.; Zhou, W.; Müller-Buschbaum, P.; Zhong, Q. High efficiency of in-situ cross-linking and acid triggered drug delivery by introducing tobramycin into injectable and biodegradable hydrogels. Colloids and Surfaces B-biointerfaces. 2022, 218, 112756.(SCI二区，Top期刊)

[3] Gao,K.; Xu, K*. Advancements and prospects of pH-responsive hydrogels in Biomedicine. Gels.2025,11(4), 293-318.(SCI二区)

[4] Wang, J.; Chen, Y.; An, J.; Xu, K.; Chen, T.; Müller-Buschbaum, P.; Zhong, Q. Intelligent Textiles with Comfort Regulation and Inhibition of Bacterial Adhesion Realized by Cross-Linking Poly(n-isopropylacrylamide-co-ethyleneglycol methacrylate) to Cotton Fabrics. ACS Appl Mater Interfaces. 2017, 9(15), 13647-13656.(SCI二区)

[5] Li, B.; Zhong, Q.; Li, D.; Xu, K.; Zhang, L.; Wang, J. Influence of Ethylene Glycol Methacrylate to the Hydration and Transition Behaviors of  Thermo-Responsive Interpenetrating Polymeric Network Hydrogels. Polymers. 2018, 10(2) 128. (SCI三区)

[6] Yang, Z# ; Zhang, QZ #; Xu, K#; Shan, JJ ; Shen, JJ ; Liu, LM; Xu, YM ; Xia, F; Bie, P; Zhang, X; Cui, YH; Bian, XW ; Qian, C. Combined Therapy with CIK Cells and Oncolytic Adenovirus Expressing IL-12 Induces Synergistic Antitumor Activity in an Experimental Tumor Model. PLOS ONE.2012,7(9), e44802,（SCI三区）

[7] Wei, XB ; Wang, G ; Li, W ; Hu, XP ; Huang, QH ; Xu, K ; Lou, WJ ; Wu, J ; Ling, C; Lou, QB ; Qian, C ; Liu, L. Activation of the JAK-STAT3 pathway is associated with the growth of colorectal carcinoma cells. Oncol Rep.2014,31(1), 335-341,(SCI三区）

[8] Wei, XB; Liu, L ; Wang, G ; Li, W ; Xu, K ; Qi, HY; Liu, H ; Shen, J ; Li, ZJ ; Shao, JM. Potent antitumor activity of theAd5/11 chimeric oncolytic adenovirus combined with interleukin-24 for acute myeloid leukemia via induction of apoptosis. Oncol Rep. 2015,33(1), 111-118（ SCI三区）

[9] Ding, Y.; Zhang, C.; Cai, G.; Xu, K.; Wu, J.; Zheng, J.; Wang, J. A facile preparation of cotton fabric containing hybrid poly(sodium methacrylate)/silver nanoparticles for oil removal and water disinfection. Textile Research Journal. 2019, 89(23-24), 5096-5107. (SCI四区)

[10] Li, B.; Li, D.; Yang, Y.; Zhang, L.; Xu, K.; Wang, J. Study of thermal-sensitive alginate-Ca2+/poly(N-isopropylacrylamide)hydrogels supported by cotton fabric for wound dressing applications. Textile Research Journal. 2018, 89(5), 801-813. (SCI四区)

[11] Wei, XB ; Liu, L ; Wang, G ; Li, W ; Xu, K; Hu, XP; Qian, C; Shao, JM.Targeting eradication of chronic myeloid leukemia using chimeric oncolytic adenovirusto drive IL-24 expression. Int J Clin Exp Pathol. 2015,8(4),3775-3784.（SCI四区）

承担及参与科研项目：

纵向：

1、教育部重点实验室优秀青年人才培养基金：具有抗菌和温敏特性医用纺织敷料的制备及其药物控释机制和创面愈合效果的研究 1/1，1万

2、浙江省自然科学基金：基于活体成像技术构建肺癌小鼠模型开展溶瘤腺病毒和pH响应凝胶协同抑癌的研究 1/5，10万

3、国家自然科学基金国际（地区）合作与交流项目： 构建具有毛囊及血管结构的皮肤组织工程材料的研究 2/6，18万

4、国家自然科学基金面上：近红外光按需驱动体液泵送和抗菌功能 Janus 纳米纤维膜的构筑及其作用机制研究 3/8，70万

5、浙江省自然科学基金：基于JAK-STAT信号通路开展岩大戟内酯B协同SOCS3 基因抑制肿瘤机制新作用靶点研究 4/6，8万

6、浙江省自然科学基金：核糖核苷酸还原酶翻译后乙酰化修饰调节机制的研究 3/4，8万

横向：

1、一种新型明胶基海绵的关键技术研发，1/5、6万

2、酵母多肽快速鉴定及促细胞增殖活力检测方法的研究，4/7、4万

3、天然高比例木棉纤维混纺功能性纱发及产业化 3/19,  175万

4、CD19 和 CD123 双靶向 CAR-T 细胞治疗白血病的临床前研究 4/5，100 万

5、抗菌性餐厨家纺及文创产品研发 3/4, 5万