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夏鹏国 博士，清华大学博士后，副教授，硕士生导师 所在学科组：植物学与药用资源学 电子邮件：xpg_xpg@126.com |
主要从事：(1)中药资源质量评价及其形成的机理研究；（2）中药资源开发。近年来，先后主持国家自然科学基金、浙江省基础公益项目、中国博士后科学基金特别资助和面上资助等科研项目，截止2021年底，发表论文50余篇，其中第一/通讯作者SCI论文20余篇（Top期刊6篇），单篇最高被引200余次，被下载8000余次。目前担任植物学经典期刊 Protoplasma (JCR Q2) 副主编 (Associate Editor)，《Chinese Herbal Medicine》青年编委，《Physiology and Molecular Biology of Plants 》、《Journal of Experimental Botany》、《Industrial Crops and Products》和《RSC Advances》等期刊特约审稿人。
主要学习工作经历
1) 2006.09—2010.07 西北农林科技大学 本科
2) 2010.09—2015.12 西北农林科技大学（保送硕博连读） 理学博士（导师：梁宗锁 教授）
3) 2018.07-2020.08 清华大学 博士后（导师：隋森芳院士，周海梦 省特级专家）
4) 2019.04-2019.07 新西兰梅西大学 访问学者
5) 2015.12-至今 浙江理工大学生命科学与医药学院
获奖与荣誉
1. 浙江理工大学先进工作者；2. 浙江理工大学就业创业先进个人；3. 博士研究生国家奖学金；4. 全国林科优秀毕业生。
科研教学项目
1) 国家自然科学基金项目“三七皂苷生物合成关键酶基因PnSS、PnSE转录调控的分子机制（81703641）”，2018.01-2020.12，主持；
2) 浙江省基础公益技术研究项目““浙八味之三叶青”质量评价关键技术研究及应用（LGN19H280004）”，2019.01-2021.12，主持；
3) 中国博士后科学基金特别资助（2020T130601），2020.05-2020.09，主持；
4) 中国博士后科学基金面上资助（2019M652146），2019.05-2020.08，主持；
5) 中央本级重大增减支项目“名贵中药资源可持续利用能力建设项目”子课题（2060302-1907-02），2019.09-2021.12，主持；
6) 浙江省重点高校建设优势特色学科开放基金“三叶青抗菌疗效形成的物质基础研究（ZYAOXYB2019004）”2019.10-2021.09，主持；
7) 浙江理工大学科研启动项目“三种人参属近缘种的遗传多样性及其遗传距离的研究（16042094-Y）”，2016-2018，主持；
8) 横向科研项目“三叶青种质分类、代谢指纹及活性成分分析（17040172-J）”，2017.06-2018.06，主持；
9) 国家自然科学基金面上项目“DNA甲基化和去甲基化协同调控丹参酚酸类成分积累的分子机制（81973415）”，2020.01-2023.12，主要参与人3/8;
10) 国家自然科学基金面上项目“异源基因组渗入系与AB-QTL分析法挖掘藏丹参特异药用种质（31871694）”，2019.01-2022.12，主要参与人3/10;
11) 国家自然科学基金面上项目“丹参SmMYB36转录因子正负调控丹参酮和丹酚酸积累的差异机制（81773835）”，2018.01-2021.12，主要参与人2/7;
发表部分论文
Ø Wanying Hu, Pengguo Xia*, Zongsuo Liang. Molecular cloning and structural analysis of key enzymes in Tetrastigma hemsleyanum for resveratrol biosynthesis. International Journal of Biological Macromolecules, 2021, 190: 19-32.
Ø Pengguo Xia*, Qianqian Li, Zongsuo Liang*, Xuemin Zhang, Kaijing Yan. Spaceflight breeding could improve the volatile constituents of Andrographis paniculata. Industrial Crops and Products, 2021, 171 (113967):1-9.
Ø Qinxiang Chang, Yan Li, Pengguo Xia* & Xiang Chen. The complete chloroplast genome of Aster sampsonii (Hance) Hemsl, a perennial herb. Mitochondrial DNA Part B-Resources, 2021, 6:9, 2594-2595.
Ø Bingxue Zhang, Pengguo Xia*, Haizheng Yu, Wenrui Li, Weiguo Chai, Zongsuo Liang*. Based on the whole genome clarified the evolution and expression process of fatty acid desaturase genes in three soybeans. International Journal of Biological Macromolecules, 2021, 182: 1966-1980.
Ø Caijuan Zhang, Pengguo Xia*, Rui Wu & Dennis Mans. The complete chloroplast genome of Scutellaria meehanioides (Lamiaceae) from Shaanxi Province, China. Mitochondrial DNA Part B-Resources, 2021, 6(6), 1685-1686.
Ø Wanying Hu, Yujie Zheng, Pengguo Xia*, Zongsuo Liang. The research progresses and future prospects of Tetrastigma hemsleyanum Diels et Gilg: A valuable Chinese herbal medicine. Journal of ethnopharmacology, 2021, 271: 113836..
Ø Yujie Zheng, Rongyu Shao, Pengguo Xia*, Zongsuo Liang, Kaijing Yan. Activity and function studies of the promoter cis-acting elements of the key enzymes in saponins biosynthesis of DS from Panax notoginseng. Protoplasma，2022，259: 163–171.
Ø Xiang Chen, Qinxiang Chang, Pengguo Xia*, Zongsuo Liang, Kaijing Yan. The complete chloroplast genome of Clematis henryi var. ternata (Ranunculaceae). Mitochondrial DNA Part B-Resources, 2021, 6(4), 1319-1320.
Ø Yujie Zheng, Pengguo Xia*, Hongguang Zhao, Jianfen Zheng, Weiguo Chai, Zongsuo Liang*, Kaijing Yan. Suitable soil moisture contents for water use efficiency and saponins accumulation in Panax notoginseng. Chinese Herbal Medicines, 2021, 13(2), 267-273.
Ø Yujie Zheng, Pengguo Xia*, Weiguo Chai, Zongsuo Liang, Kaijing Yan. Accumulation dynamics of elements in Panax notoginseng during its whole growing seasons. Industrial Crops and Products, 2020, 158:1-10.
Ø Pengguo Xia*, Wanying Hu, Tongyao Liang, Dongfeng Yang and Zongsuo Liang*. An attempt to establish an Agrobacterium-mediated transient expression system in medicinal plants. Protoplasma 2020, 257, 1497-1505.
Ø Pengguo Xia*; Yujie Zheng, Zongsuo Liang*. Structure and Location Studies on Key Enzymes in Saponins Biosynthesis of Panax notoginseng. International Journal of Molecular Sciences, 2019, 20(24), 6121.
Ø Yu Zhang, Yujie Zheng, Pengguo Xia*, Lulu Xun and Zongsuo Liang*. Impact of continuous Panax notoginseng plantation on soil microbial and biochemical properties. Scientific reports, 9, 13205 (2019).
Ø Renjun Mao#, Pengguo Xia#, Jingling Liu, Xin Li, Ruilian Han, Fenghua Liu, Hongguang Zhao, Zongsuo Liang*. Genetic diversity and population structure assessment of Chinese Senna obtusifolia L. by molecular markers and morphological traits of seed. Acta Physiologiae Plantarum, 2018, 40(12):1-14.
Ø Pengguo Xia, Hongbo Guo, Mei Ru, Dongfeng Yang, Zongsuo Liang*, Xijun Yan, Yan Liu. Accumulation of saponins in Panax notoginseng during its growing seasons. Industrial Crops and Products, 2017, 104: 287-292.
Ø Pengguo Xia, Zhenqing Bai, Tongyao Liang, Dongfeng Yang, Zongsuo Liang*, Xijun Yan, Yan Liu. High-performance liquid chromatography based chemical fingerprint analysis and chemometric approaches for the identification and distinction of three endangered Panax plants in Southeast Asia. Journal of Separation Science, 2016, 39(20): 3880-3888.
Ø Pengguo Xia, Hongbo Guo, Yu Zhang, Michael K. Deyholos, Liang Peng, Yanyan Jia, Xijun Yan, Yan Liu, Zongsuo Liang*. Wild Panax vietnamensis and Panax stipuleanatus markedly increase the genetic diversity of Panax notoginseng (Araliaceae) revealed by start codon targeted (SCoT) markers and ITS DNA barcode. Biochemical Systematics and Ecology, 2016, 66: 37–42.
Ø Pengguo Xia, Hongbo Guo, Hongguang Zhao, Jie Jiao, Michael K. Deyholos, Xijun Yan, Yan Liu, Zongsuo Liang*. Optimal fertilizer application for Panax notoginseng and effect of soil water on root rot disease and saponin contents. Journal of Ginseng Research, 2016, 40(1): 38-46.
Ø Pengguo Xia, Jiazhou Li, Ruilin Wang, Yu Zhang, Hongbo Guo, Xijun Yan, Yan Liu, Zongsuo Liang*. Comparative study on volatile oils of four Panax genus species in Southeast Asia by gas chromatography-mass spectrometry. Industrial Crops and Products, 2015, 74: 478-484.
Ø Pengguo Xia, Hongbo Guo, Zongsuo Liang*, Xiuming Cui, Yan Liu, Fenghua Liu. Nutritional composition of Sanchi (Panax notoginseng) seed and its potential for industrial use. Genetic Resources & Crop Evolution, 2014, 61(3): 663-667.
Ø Xiaomei Yu, Lingli Chen, Bo Lin, Li Zhang, Xue Yang, Xiaobin Liu, Pengguo Xia, Yueming Liu, Shaoxiong Zheng, Xiumei Zhou, Yigang Wang, Yuan Qin, Liang Wang, ZhigangHe Hu, Biao QiangHuang. Establishment of Galectin-3 Time-resolved Fluoroimmunoassay and its Application in Idiopathic Membranous Nephropathy. Journal of fluorescence, 2022, 1, 1800.
Ø Peng Zhan, Feiyang Wang, Pengguo Xia, Guanghua Zhao, Meitang Wei, Fugang Wei, Ruilian Han*. Assessment of suitable cultivation region for Panax notoginseng under different climatic conditions using MaxEnt model and high-performance liquid chromatography in China. Industrial Crops and Products, 2022, 176, 114416.
Ø Qingqing Wu, Chen Hang, Ting Li, Binrong Wang, Yuan Qin, Yigang Wang, Xiumei Zhou, Pengguo Xia, Huiming Sheng*, Pei Huang*, Biao Huang*. Establishment of time-resolved fluoroimmunoassay of IgG4 based on magnetic microspheres. Journal of Clinical Laboratory Analysis, 2021, e23874.
Ø Biao Huang, Jian Wu, Hao Chen, Li Zhang, Xiumei Zhou, Qingqing Wu, Ting Li, Yigang Wang, Pengguo Xia, Yaping Dai, Guoyin Kai, Pengfei Liu, Hao Pei. Establishment and Application of a Dual-Labeling Time-Resolved Fluorescence Immunoassay Method for Simultaneous Detection of the Troponin I-C Complex and Full-Size-Troponin I. Frontiers in Cardiovascular Medicine, 2021, 7, 596051.
Ø Li Zhang; Xiumei Zhou, Yaping Dai, Chunyan Lv, Jian Wu, Qingqing Wu, Ting Li, Yigang Wang, Pengguo Xia, Hao Pei, Biao Huang. Establishment of interleukin-18 time-resolved fluorescence immunoassay and its preliminary application in liver disease. Journal of Clinical Laboratory Analysis, 2021, e23758.
Ø Feiyan Wang, Huaqian You, Yanhong Guo, Yukun Wei, Pengguo Xia, Zongqi Yang, Min Ren, Hui Guo, Ruilian Han, Dongfeng Yang. Essential oils from three kinds of fingered citrons and their antibacterial activities. Industrial Crops and Products, 2020, 147:1-10.
Ø Renjun Mao, Wenrui Li, Zhigui He, Zhenqing Bai, Pengguo Xia, Zongsuo Liang, Yan Li. Physiological, transcriptional, and metabolic alterations in spaceflight-subjected Senna obtusifolia. Plant Physiology and Biochemistry, 2019, 139: 33-43.
Ø Dongfeng Yang, Zhicheng Huang, Weibo Jin, Pengguo Xia, Qiaojun Jia, Zongqi Yang, Zhuoni Hou, Haihua Zhang, Wei Ji, Ruilian Han. DNA methylation: A new regulator of phenolic acids biosynthesis in Salvia miltiorrhiza. Industrial Crops and Products, 2018, 124: 402-411.
Ø Jie Jiao, Zhenqing Bai, Wenli Huang, Pengguo Xia, Feng Liu, Cunde Ma, Zongsuo Liang*. Evaluation of genetic diversity and population structure of polygonati rhizoma germplasms: implications for better crop development and conservation of a traditional Chinese medicine. Acta Physiologiae Plantarum, 2018, 40(10):184.
Ø Zhenqing Bai, Wenrui Li, Yanyan Jia, Zhiyong Xue, Jie Jiao, Wenli Huang, Pengguo Xia, Zongsuo Liang*. The ethylene response factor SmERF6 co-regulates the transcription of SmCPS1 and SmKSL1 and is involved in tanshinone biosynthesis in Salvia miltiorrhiza hairy roots[J]. Planta, 2018:1-13.
Ø Dongfeng Yang, Yumin Fang, Pengguo Xia, Xiaodan Zhang, Zongsuo Liang*. Diverse responses of tanshinone biosynthesis to biotic and abiotic elicitors in hairy root cultures of Salvia miltiorrhiza and Salvia castanea Diels f. tomentosa. Gene, 2018, 643: 61–67.
Ø Renjun Mao, Pengguo Xia, Zhigui He, Yan Liu, Fenghua Liu, Hongguang Zhao, Ruilian Han, Zongsuo Liang*. Identification of seeds based on molecular markers and secondary metabolites in Senna obtusifolia and Senna occidentalis. Botanical Studies, 2017, 58(1):43.
Ø Zhenqing Bai, Pengguo Xia, Ruilin Wang, Jie Jiao, Mei Ru, Jingling Liu, Zongsuo Liang*. Molecular cloning and characterization of five SmGRAS genes associated with tanshinone biosynthesis in Salvia miltiorrhiza hairy roots. Plos One, 2017, 12(9):e0185322.
Ø Yong Wang, Jing Yu, Pengguo Xia, Ziyun Zhou, Ruilian Han, Zongsuo Liang*. Artemisia dominant species succession relating to the soil moisture decrease in abandoned land of the Loess Plateau (China): comparative study of drought-adaptive characteristics. SpringerPlus, 2016, 5(1):1-21.
Ø Shuncang Zhang, Hongyan Li, Xiao Liang, Yan Yan, Pengguo Xia, Yanyan Jia, Zongsuo Liang*. Enhanced production of phenolic acids in Salvia miltiorrhiza hairy root cultures by combing the rnai-mediated silencing of chalcone synthase gene with salicylic acid treatment. Biochemical Engineering Journal, 2015, 103: 185–192.
Ø Liang Peng, Mei Ru, Kunru Wang, Bo Li, Yancui Wang, Pengguo Xia, Zongsuo Liang*. Spaceflight Environment-Induced Variation in Root Yield and Active Constituents of Salvia miltiorrhiza. Planta Medica, 2014, 80(12):1029-1035.
Ø 赵宏光, 胡婉莹, 郑宇婕, 张晨, 梁宗锁, 夏鹏国*. 不同储存温度和方式对丹参种子萌发的影响[J] .种子, 2020, 39(11): 14-18+43.
Ø 陈曦, 夏鹏国*, 于靖*, 王珺, 胡新文, 陈健妙, 吴友根, 周开兵, 赖杭桂.越南油茶胚状体的培养及其酚类物质含量测定[J]. 热带农业工程, 2018, 42(06): 1-6.
Ø 韩蕊莲, 余前进, 白晓林, 韦美膛, 郑建芬, 梁宗锁, 夏鹏国*.施用微肥对三七生长及有效成分积累的影响[J]. 时珍国医国药, 2018(9): 2243-2247.
Ø 陈黎明, 罗美佳, 夏鹏国*, 杨东风，梁宗锁*. 光强对三七生长、光合特性及有效成分积累的影响[J]. 时珍国医国药, 2016(12): 3004-3006.
Ø 夏鹏国, 张顺仓, 梁宗锁*, 齐志鸿. 三七化学成分的研究历程和概况. 中草药, 2014, 45(17): 2564-2570.
Ø 夏鹏国, 崔秀明, 韦美膛, 刘峰华, 梁宗锁*. 三七的生物学特性研究进展. 中药材, 2012, 35(5): 831-835.
Ø 孙佳秀, 夏鹏国, 梁宗锁. 荷叶的药理功效及功能食品开发[J]. 浙江农业科学. 2021,62(09): 1874-1881.
Ø 张雪梅, 张刘伟, 左小容, 夏鹏国, 梁宗锁*. 丹参趁鲜加工关键技术与质量影响研究[J]. 保鲜与加工, 2021, 21(07): 45-51.
Ø 蒋梦丹, 夏鹏国, 梁宗锁, 许鑫瀚, 陈喜良, 韩蕊莲. 基于显微结构、抗氧化活性和化学成分的三叶青须根入药的可行性研究. 时珍国医国药, 2020(10): 2492-2495.
Ø 王艳婷, 郭妍宏, 王飞艳, 方誉民, 夏鹏国, 梁宗锁, 杨东风*.丹参和藏丹参毛状根MYB和bHLH转录因子基因表达差异研究. 浙江农业科学, 2019,60(09):1593-1600
Ø 张顺仓, 夏鹏国, 王幼平,梁宗锁*. 丹参中转录因子基因SmMYB-like 1的克隆和表达分析. 扬州大学学报(农业与生命科学版), 2017, 38(3), 32-38.
Ø 郭宏波, 张跃进, 梁宗锁, 夏鹏国. 水旱轮作减轻三七连作障碍的潜势分析. 云南农业大学学报, 2017, V32(1):161-169.
Ø 张宇, 周自云, 夏鹏国, 梁宗锁*, 刘书礼, 刘之良. 干旱胁迫对柴胡中皂苷合成关键酶基因表达及皂苷含量的影响. 中国中药杂志, 2016, 41(4):643-647.
Ø 魏良柱, 邢丙聪, 孙瑞泽, 夏鹏国, 赵宏光, 梁宗锁, 舒志明*. 商洛地区丹参种子质量现状分析及评价方法建立. 种子, 2016, 35(3):89-92.
Ø 赵宏光, 夏鹏国, 韦美膛, 刘峰华, 张晨, 梁宗锁*. 土壤水分含量对三七根生长、有效成分积累及根腐病发病率的影响. 西北农林科技大学学报(自然科学版), 2014, 42(2): 173-178.
Ø 罗美佳, 夏鹏国, 齐志鸿, 张小红*, 陈中坚, 刘岩, 刘峰华, 梁宗锁. 光质对三七生长、光合特性及有效成分积累的影响. 中国中药杂志, 2014, 39(4): 610-613.
指导研究生获奖情况：
u 郑宇婕：研究生期间获得研究生国家奖学金、浙江省高校优秀毕业生、浙江理工大学优秀毕业生、研究生优秀学位论文培育基金等荣誉，学位论文获得浙江理工大学优秀研究生学位论文。
u 胡婉莹：研究生期间获得研究生国家奖学金、浙江省高校优秀毕业生、浙江理工大学优秀毕业生、校三好学生等荣誉称号，申请至浙江大学农业与生物技术学院2022级博士研究生。
目前在读研究生：
李倩倩、章彩娟、陈享、张婷婷、毛雨程
