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副教授

李欧

发表于:2016-06-22浏览人数:

别:男

出生年月:198002

称:讲师

微生物

室: 6-443

话: 86843195

电子邮件:ouli@zstu.edu.cn

主要学习工作经历

1.2014/6 - 至今,浙江理工大学,生命科学学院,讲师

2.2011/9 - 2014/6,浙江大学,微生物学,博士

3.2005/9 - 2011/6,浙江海正药业股份有限公司

4. 2002/9 - 2005/6,浙江大学,遗传学,硕士

5. 1998/9 - 2002/6,浙江大学,生物科学,学士

主要学术及社会兼职

1. 浙江省微生物学会会员

主要研究方向

1. 微生物资源及活性物质(抗菌、抗糖尿病活性成及活性多糖)开发和利用

2. 微生物菌剂的开发和利用

3. 微生物法污水处理

获奖与荣誉

1. 2015届毕业设计(论文)优秀指导教师

科研教学项目

1.浙江省自然科学基金面上项目,一种特殊类芽孢杆菌胞外多糖生物合成途径研究,201501-201712,主持

2.国家自然科学基金面上项目,31370132、基因组变构改进酵母胁迫耐性等复杂表型的分子机理、201401-201712参加

3.国家自然科学基金青年科学基金项目,41306095、食物链对腹泻性贝类毒素产毒藻鳍藻生长和产毒的调控研究、201401-201612、参加

4.重大横向(研究经费100万),结冷胶生产的菌株与发酵提取工艺技术优化研究、201101-201312、第二负责人

5.重大横向(研究经费130万),国家一类抗生素新药研发、200801-201112、第二负责人

6.重大横向(研究经费100万),抗病功能基因的克隆表达及国家新药开发、200801-201112、第二负责人

7.重大横向(研究经费330万),超常态高效益生物燃料乙醇大规模生产关键技术、第二负责人

8. 重大横向(研究经费330万),酵母培养新技术体系的创建及其在酒精生产节能中的应用、第二负责人

专著论文

1.Li, O., C.D. Qian, D.Q. Zheng, P.M. Wang, Y. Liu, X.H. Jiang, X.C. Wu, Two UDP-glucuronic acid decarboxylases involved in the biosynthesis of a bacterial exopolysaccharide in Paenibacillus elgii. Applied Microbiology and Biotechnology, 2015. 99:3127-3139

2.Li, O., C. Lu, A. Liu, L. Zhu, P.-M. Wang, C.-D. Qian, X.-H. Jiang,X.-C. Wu, Optimization and characterization of polysaccharide-based bioflocculant produced by Paenibacillus elgii B69 and its application in wastewater treatment. Bioresource Technology, 2013. 134: 87-93.

3.Li, O., A. Liu, C. Lu, D.Q. Zheng, C.D. Qian, P.M. Wang, X.H. Jiang,X.C. Wu, Increasing viscosity and yields of bacterial exopolysaccharides by repeatedly exposing strains to ampicillin. Carbohydrate Polymers, 2014. 110: 203-8.

4.Wu, X.C., O. Li, Y.M. Chen, L. Zhu, C.D. Qian, Y. Teng,X.L. Tao, A carotenoid-free mutant strain of Sphingomonas paucimobilis ATCC 31461 for the commercial production of gellan. Carbohydrate Polymers, 2011. 84(3): 1201-1207.

5.Wen, Y., X. Wu, Y. Teng, C. Qian, Z. Zhan, Y. Zhao, O. Li, Identification and analysis of the gene cluster involved in biosynthesis of paenibactin, a catecholate siderophore produced by Paenibacillus elgii B69. Environmental Microbiology, 2011. 13(10): 2726-2737.

6.李欧,尤红,梁宗锁,杨东风,胡秀芳,杨随娟,杨瑞环,张露,班善,苏尚健,沈书立,具有诱导丹参毛状根酚酸积累作用的内生菌及其用途,中国专利,申请号:201510176190.7

7.李欧,尤红,梁宗锁,杨东风,胡秀芳,杨瑞环,杨随娟,班善,沈书立,张露,苏尚健,微杆菌及其用途,中国专利,申请号:201510178094.6

8.李欧,郑道琼,鲁翠,刘傲,吴雪昌,一种提高细菌多糖产量及粘度的培养方法,中国专利,CN201310237997.8

9.李欧,刘傲,鲁翠,朱亮,钱朝东,吴雪昌,一株类芽孢杆菌及其产生的微生物胞外多糖絮凝剂及应用,中国专利,CN201210545371.

10.Zhu, LiangWu, XuechangLi, OuQian, ChaodongGao, HaichunCloning and characterization of genes involved in nostoxanthin biosynthesis of Sphingomonas elodea ATCC 31461.PLos One201274):e35099-e35099

11.Zhu, LiangWu, XuechangLi, OuChen, YaminQian, ChaodongTeng, YiTao, XianglinGao, HaichunCloning and knockout of phytoene desaturase gene in Sphingomonas elodea ATCC 31461 for economic recovery of gellan gum.J Ind Microbiol Biotechnol2011389):1507-1513

12.Teng, YiZhao, WenpengQian, ChaodongLi, OuZhu, LiangWu, XuechangGene cluster analysis for the biosynthesis of elgicins, novel lantibiotics produced by Paenibacillus elgii B69.BMC Microbiology20121245-45

13.Ding, RuiWu, Xue-Chang*Qian, Chao-DongTeng, YiLi, OuZhan, Zha-JunZhao, Yu-HuaIsolation and identification of lipopeptide antibiotics from Paenibacillus elgii B69 with inhibitory activity against methicillin-resistant Staphylococcus aureus.Journal of Microbiology2011496):942-949

14.吴雪昌,吴荣明,李欧,朱亮,陈亚敏,钱朝东,陈梅,黄色素生成缺陷鞘脂单胞菌及其在结冷胶生产中的应用,中国专利,CN200910153005.7(申请PCT国际专利)

15.吴雪昌,朱亮,李欧,少动鞘氨醇单胞菌的crtZ基因、crtG基因及其应用,中国专利,CN201110183602.1 专利

16.吴雪昌,朱亮,李欧,少动鞘氨醇单胞菌的八氢番茄红素脱氢酶基因及其应用,中国专利,CN201010506928.9

17.吴雪昌,朱亮,李欧,少动鞘氨醇单胞菌的番茄红素环化酶基因及其应用,中国专利,CN201110184745.4

18.Qian, C.D., T.Z. Liu, S.L. Zhou, R. Ding, W.P. Zhao, O. Li, X.C. Wu, Identification and functional analysis of gene cluster involvement in biosynthesis of the cyclic lipopeptide antibiotic pelgipeptin produced by Paenibacillus elgii. BMC Microbiology, 2012. 12.

19.吴雪昌,钱朝东,李欧,方海环,周建英,白骅,杜加秋,林建秋,一种多烯大环内酯类化合物及其制备与应用,中国专利,CN200910153060.6

20Wu, X.C., Y.M. Chen, Y.D. Li, O. Li, L. Zhu, C.D. Qian, X.L. Tao,Y. Teng, Constitutive expression of Vitreoscilla haemoglobin in Sphingomonas elodea to improve gellan gum production. Journal of Applied Microbiology, 2011. 110(2): 422-430.