目前主要从事药用植物资源开发及其次生代谢物合成与分子调控相关的科研工作。近年来,已主持和参加多项国家自然科学基金、浙江省自然科学基金等科研项目,并在《Industrial Crops and Products》、《Journal of Ginseng Research》、《Journal of Separation Science》、《Plos One》、《Genetic Resources & Crop Evolution》等国际期刊发表文章十余篇。担任多个期刊审稿人:Physiology and Molecular Biology of Plants (PMBP)、Industrial Crops and Products、RSC Advances。
主要学习工作经历
1) 2006.09—2010.07 西北农林科技大学 本科
2) 2010.09—2015.12 西北农林科技大学(保送硕博连读) 理学博士(导师:梁宗锁 教授)
3) 2018.07-2020.08 清华大学 博士后(导师:隋森芳院士,周海梦 省特级专家)
4) 2019.04-2019.07 新西兰梅西大学 访问学者
5) 2015.12-2018.12 浙江理工大学生命科学与医药学院 讲师
6) 2019.01-2019.12 浙江理工大学生命科学与医药学院 特聘副教授
7) 2020.01-至今 浙江理工大学生命科学与医药学院 副教授
主要研究方向
1. 中药资源开发和质量评价;2. 药用植物次生代谢及其调控。
获奖与荣誉
1. 浙江理工大学先进工作者;2. 浙江理工大学就业创业先进个人;3. 博士研究生国家奖学金。
科研教学项目
1) 国家自然科学基金青年项目“三七皂苷生物合成关键酶基因PnSS、PnSE转录调控的分子机制(81703641)”,2018.01-2020.12,主持;
2) 浙江省基础公益技术研究项目““浙八味之三叶青”质量评价关键技术研究及应用(LGN19H280004)”,2019.01-2021.12,主持;
3) 中央本级重大增减支项目“名贵中药资源可持续利用能力建设项目”子课题(2060302-1907-02),2019.09-2021.12,主持;
4) 浙江省教育厅一般科研项目“皂苷合成关键酶基因SS和SE的挖掘及其细胞定位研究(Y201738462)”,2017.09-2019.10,主持;
5) 浙江省重点高校建设优势特色学科开放基金“三叶青抗菌疗效形成的物质基础研究(ZYAOXYB2019004)”2019.10-2021.09,主持;
6) 浙江理工大学科研启动项目“三种人参属近缘种的遗传多样性及其遗传距离的研究(16042094-Y)”,2016-2018,主持;
7) 横向科研项目“三叶青种质分类、代谢指纹及活性成分分析(17040172-J)”,2017.06-2018.06,主持;
8) 国家自然科学基金面上项目“DNA甲基化和去甲基化协同调控丹参酚酸类成分积累的分子机制(81973415)”,2020.01-2023.12,主要参与人3/8;
9) 国家自然科学基金面上项目“异源基因组渗入系与AB-QTL分析法挖掘藏丹参特异药用种质(31871694)”,2019.01-2022.12,主要参与人3/10;
10) 国家自然科学基金面上项目“丹参SmMYB36转录因子正负调控丹参酮和丹酚酸积累的差异机制(81773835)”,2018.01-2021.12,主要参与人2/7;
专著论文
Pengguo Xia*; Yujie Zheng, Zongsuo Liang. Structure and Location Studies on Key Enzymes in Saponins Biosynthesis of Panax notoginseng. International Journal of Molecular Sciences, 2019, 20(24), 6121. (JCR二区)
Yu Zhang, Yujie Zheng, Pengguo Xia*, Lulu Xun and Zongsuo Liang. Impact of continuous Panax notoginseng plantation on soil microbial and biochemical properties. Scientific reports, 9, 13205 (2019). (JCR三区)
Renjun Mao#, Pengguo Xia#, Jingling Liu, Xin Li, Ruilian Han, Fenghua Liu, Hongguang Zhao, Zongsuo Liang*. Genetic diversity and population structure assessment of Chinese Senna obtusifolia L. by molecular markers and morphological traits of seed. Acta Physiologiae Plantarum, 2018, 40(12):1-14. (JCR三区)
Pengguo Xia, Hongbo Guo, Mei Ru, Dongfeng Yang, Zongsuo Liang*, Xijun Yan, Yan Liu. Accumulation of saponins in Panax notoginseng during its growing seasons. Industrial Crops and Products, 2017, 104: 287-292. (JCR一区)
Pengguo Xia, Zhenqing Bai, Tongyao Liang, Dongfeng Yang, Zongsuo Liang*, Xijun Yan, Yan Liu. High-performance liquid chromatography based chemical fingerprint analysis and chemometric approaches for the identification and distinction of three endangered Panax plants in Southeast Asia. Journal of Separation Science, 2016, 39(20): 3880-3888.(JCR三区)
Pengguo Xia, Hongbo Guo, Yu Zhang, Michael K. Deyholos, Liang Peng, Yanyan Jia, Xijun Yan, Yan Liu, Zongsuo Liang*. Wild Panax vietnamensis and Panax stipuleanatus markedly increase the genetic diversity of Panax notoginseng (Araliaceae) revealed by start codon targeted (SCoT) markers and ITS DNA barcode. Biochemical Systematics and Ecology, 2016, 66: 37–42.(JCR四区)
Pengguo Xia, Hongbo Guo, Hongguang Zhao, Jie Jiao, Michael K. Deyholos, Xijun Yan, Yan Liu, Zongsuo Liang*. Optimal fertilizer application for Panax notoginseng and effect of soil water on root rot disease and saponin contents. Journal of Ginseng Research, 2016, 40(1): 38-46.(JCR二区)
Pengguo Xia, Jiazhou Li, Ruilin Wang, Yu Zhang, Hongbo Guo, Xijun Yan, Yan Liu, Zongsuo Liang*. Comparative study on volatile oils of four Panax genus species in Southeast Asia by gas chromatography-mass spectrometry. Industrial Crops and Products, 2015, 74: 478-484.(JCR一区)
Pengguo Xia, Hongbo Guo, Zongsuo Liang*, Xiuming Cui, Yan Liu, Fenghua Liu. Nutritional composition of Sanchi (Panax notoginseng) seed and its potential for industrial use. Genetic Resources & Crop Evolution, 2014, 61(3): 663-667.(JCR三区)
Renjun Mao, Wenrui Li, Zhigui He, Zhenqing Bai, Pengguo Xia, Zongsuo Liang, Yan Li. Physiological, transcriptional, and metabolic alterations in spaceflight-subjected Senna obtusifolia. Plant Physiology and Biochemistry, 2019, 139: 33-43.
Dongfeng Yang, Zhicheng Huang, Weibo Jin, Pengguo Xia, Qiaojun Jia, Zongqi Yang, Zhuoni Hou, Haihua Zhang, Wei Ji, Ruilian Han. DNA methylation: A new regulator of phenolic acids biosynthesis in Salvia miltiorrhiza. Industrial Crops and Products, 2018, 124: 402-411.
Jie Jiao, Zhenqing Bai, Wenli Huang, Pengguo Xia, Feng Liu, Cunde Ma, Zongsuo Liang*. Evaluation of genetic diversity and population structure of polygonati rhizoma germplasms: implications for better crop development and conservation of a traditional Chinese medicine. Acta Physiologiae Plantarum, 2018, 40(10):184.
Zhenqing Bai, Wenrui Li, Yanyan Jia, Zhiyong Xue, Jie Jiao, Wenli Huang, Pengguo Xia, Zongsuo Liang*. The ethylene response factor SmERF6 co-regulates the transcription of SmCPS1 and SmKSL1 and is involved in tanshinone biosynthesis in Salvia miltiorrhiza hairy roots[J]. Planta, 2018:1-13.
Dongfeng Yang, Yumin Fang, Pengguo Xia, Xiaodan Zhang, Zongsuo Liang*. Diverse responses of tanshinone biosynthesis to biotic and abiotic elicitors in hairy root cultures of Salvia miltiorrhiza and Salvia castanea Diels f. tomentosa. Gene, 2018, 643: 61–67.
Renjun Mao, Pengguo Xia, Zhigui He, Yan Liu, Fenghua Liu, Hongguang Zhao, Ruilian Han, Zongsuo Liang*. Identification of seeds based on molecular markers and secondary metabolites in Senna obtusifolia and Senna occidentalis. Botanical Studies, 2017, 58(1):43.
Zhenqing Bai, Pengguo Xia, Ruilin Wang, Jie Jiao, Mei Ru, Jingling Liu, Zongsuo Liang*. Molecular cloning and characterization of five SmGRAS genes associated with tanshinone biosynthesis in Salvia miltiorrhiza hairy roots. Plos One, 2017, 12(9):e0185322.
Yong Wang, Jing Yu, Pengguo Xia, Ziyun Zhou, Ruilian Han, Zongsuo Liang*. Artemisia dominant species succession relating to the soil moisture decrease in abandoned land of the Loess Plateau (China): comparative study of drought-adaptive characteristics. SpringerPlus, 2016, 5(1):1-21.
Shuncang Zhang, Hongyan Li, Xiao Liang, Yan Yan, Pengguo Xia, Yanyan Jia, Zongsuo Liang*. Enhanced production of phenolic acids in Salvia miltiorrhiza hairy root cultures by combing the rnai-mediated silencing of chalcone synthase gene with salicylic acid treatment. Biochemical Engineering Journal, 2015, 103: 185–192.
Liang Peng, Mei Ru, Kunru Wang, Bo Li, Yancui Wang, Pengguo Xia, Zongsuo Liang*. Spaceflight Environment-Induced Variation in Root Yield and Active Constituents of Salvia miltiorrhiza. Planta Medica, 2014, 80(12):1029-1035.
陈曦, 夏鹏国*, 于靖*, 王珺, 胡新文, 陈健妙, 吴友根, 周开兵, 赖杭桂.越南油茶胚状体的培养及其酚类物质含量测定.热带农业工程,2018,42(06):1-6.
韩蕊莲, 余前进, 白晓林, 韦美膛, 郑建芬, 梁宗锁, 夏鹏国*.施用微肥对三七生长及有效成分积累的影响[J]. 时珍国医国药, 2018(9): 2243-2247.
陈黎明, 罗美佳, 夏鹏国*, 杨东风,梁宗锁*. 光强对三七生长、光合特性及有效成分积累的影响[J]. 时珍国医国药, 2016(12): 3004-3006.
夏鹏国, 张顺仓, 梁宗锁*, 齐志鸿. 三七化学成分的研究历程和概况. 中草药, 2014, 45(17): 2564-2570.
夏鹏国, 崔秀明, 韦美膛, 刘峰华, 梁宗锁*. 三七的生物学特性研究进展. 中药材, 2012, 35(5): 831-835.
郭宏波, 张跃进, 梁宗锁, 夏鹏国. 水旱轮作减轻三七连作障碍的潜势分析. 云南农业大学学报, 2017, V32(1):161-169.
张宇, 周自云, 夏鹏国, 梁宗锁*, 刘书礼, 刘之良. 干旱胁迫对柴胡中皂苷合成关键酶基因表达及皂苷含量的影响. 中国中药杂志, 2016, 41(4):643-647.
魏良柱, 邢丙聪, 孙瑞泽, 夏鹏国, 赵宏光, 梁宗锁, 舒志明*. 商洛地区丹参种子质量现状分析及评价方法建立. 种子, 2016, 35(3):89-92.
赵宏光, 夏鹏国, 韦美膛, 刘峰华, 张晨, 梁宗锁*. 土壤水分含量对三七根生长、有效成分积累及根腐病发病率的影响. 西北农林科技大学学报(自然科学版), 2014, 42(2): 173-178.
罗美佳, 夏鹏国, 齐志鸿, 张小红*, 陈中坚, 刘岩, 刘峰华, 梁宗锁. 光质对三七生长、光合特性及有效成分积累的影响. 中国中药杂志, 2014, 39(4): 610-613.